Asuka Hashino

Kumamoto University, Japan

Abstract Title:A Scoping Review of the effect of inhaled drugs on the sleep quality of COPD patients

Biography:

Asuka Hashino has completed a master’s program of Hiroshima University graduate school. She is the assistant professor at Department of nursing, Faculty of life Sciences, Kumamoto University in Japan. She is conducting research on observational studies of stress in COPD patients and nursing education for understanding patients with chronic diseases.

Research Interest:

Approximately half of patients with chronic obstructive pulmonary disease (COPD) have sleep disorders and tend to have poor sleep quality. We conducted a scoping review of the effects of bronchodilators, which are the basic treatment for COPD, on sleep quality. Using the keywords “COPD”, “sleep quality” and “inhalation”, we conducted a search of original research papers in Scopus and the Japanese Medical Abstracts Society Web Edition. As a result of the search, four documents were extracted. All four were two-group comparative studies, and three of them used the Pittsburgh Sleep Quality Index (PSQI) to evaluate sleep quality, but one used the visual analogue scale (VAS). COPD patients with sleep disorders are more likely to experience symptom improvement with LAMA + long-acting β2-agonist (LABA) administration than with LAMA/inhaled corticosteroid (ICS) administration, and COPD patients who are inhaling ICS/LABA/LAMA and have decreased sleep quality patients who are taking ICS/LABA/LAMA inhalers have poorer symptom improvement than those who are not, inhaling LABA improves arterial oxygen saturation during sleep but has no effect on sleep quality, and short-acting muscarinic antagonist (SAMA) inhalation significantly improves mean nocturnal SaO2 and sleep quality. In these previous studies, the details of inhaler usage and use conditions, and inhalation technique errors were not described in detail. For COPD patients, many of whom are elderly, the use of multiple inhalation devices and the techniques involved can be complex, and it may be difficult to maintain the correct posture, breathing, and technique. It is also necessary to verify the extent to which inhalation technique errors affect the results